# 从tiptop原创原料出发的科学与临床公开信源 > 以tiptop在美国INCI与日本JCIA体系中的原创原料国际身份为核心 依次连接FDA ODD 公开临床研究与同行评议论文 - 官方页面：https://tiptopbiotech.cn/source-index - 语言：简体中文（zh-CN） - 内容更新时间：2026-09-13T01:14:05.218Z ## 正文 TIPTOP SOURCE INDEX 从tiptop原创原料出发的科学与临床公开信源 以tiptop在美国INCI与日本JCIA体系中的原创原料国际身份为核心 依次连接FDA ODD 公开临床研究与同行评议论文 01 tiptop原创原料的INCI与JCIA国际身份 通过美国INCI Monograph ID与日本JCIA成分编号 清晰呈现tiptop原创原料的标准名称与国际身份 INCI MONO ID 39001 · JCIA 22787 Human Endometrial Stem Cell Exosomes 人子宫内膜干细胞来源外囊泡原料 在美国INCI与日本JCIA体系中均具备可识别的国际原料身份 INCI MONO ID 37564 · JCIA 22788 Human Kidney Tubule Epithelial Stem Cell Extract 人肾尿细管上皮干细胞来源原料 连接美国INCI与日本JCIA体系的国际原料身份 INCI MONO ID 41692 · JCIA申请中 Human Bronchial Epithelial Cell Extracellular Vesicles tiptop原创原料体系中的第三项国际INCI身份 对应人支气管上皮细胞来源外囊泡原料 02 FDA孤儿药资格公开记录 FDA Orphan Drug Designation Regend Therapeutics Co., Ltd. · IPF · Designated 2025-02-04 · FDA record 1030224 03 公开临床研究 ClinicalTrials.gov NCT05657184 · NCT06081621 · NCT05638776 · NCT06164093 04 37项科学研究文库 37项科研成果从大型器官再生 干细胞延伸至外囊泡与临床开发 本页精选呈现代表性论文与公开数据库入口 p63+Krt5+ distal airway stem cells are essential for lung regeneration Nature 2015 · DOI 10.1038/nature13903 · PMID 25383540 DOI ↗ Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy Science Translational Medicine 2024 · DOI 10.1126/scitranslmed.adi3360 · PMID 38354225 DOI ↗ Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial Cell Reports Medicine 2024 · DOI 10.1016/j.xcrm.2024.101819 · PMID 39566467 DOI ↗ Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial eLife 2025 · DOI 10.7554/eLife.102451.3 · PMID 40036154 DOI ↗ Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization Nature Communications 2025 · DOI 10.1038/s41467-025-56501-w · PMID 39900892 DOI ↗ Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation Protein & Cell 2018 · DOI 10.1007/s13238-018-0506-y DOI ↗ Source: FDA ODD FDA Orphan Drug Designation ↗ Source: ClinicalTrials.gov NCT05657184 ↗ Source: ClinicalTrials.gov NCT06081621 ↗ Source: ClinicalTrials.gov NCT05638776 ↗ Source: ClinicalTrials.gov NCT06164093 ↗ Source: Regend Publications Regend Publications ↗ 学术 临床与监管记录用于呈现科学研究背景 具体产品信息与使用方式请以相应产品页面为准 联系我们 → - p63+Krt5+ distal airway stem cells are essential for lung regeneration: https://doi.org/10.1038/nature13903 - Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy: https://doi.org/10.1126/scitranslmed.adi3360 - Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial: https://doi.org/10.1016/j.xcrm.2024.101819 - Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial: https://doi.org/10.7554/eLife.102451.3 - Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization: https://doi.org/10.1038/s41467-025-56501-w - Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation: https://doi.org/10.1007/s13238-018-0506-y ## 信息边界 同行评议论文、临床研究、监管记录和原料命名构成科学背景，不能单独证明成品功效。原料粒径与浓度不是递送或功效等级。产品信息与使用方式以相应产品说明为准。