我们整理并公开这37篇文献,是希望完整交代tiptop相关科研来源及持续关注的研究方向。书目涵盖肺与气道、肾脏、女性生殖道与子宫内膜、细胞信号与系统生物学、肝再生,保留正式题名、年份、期刊及DOI。

为什么把科研来源和背景文献一并保留

索引中的30篇文献显示Wei Zuo参与署名,我们将其列为科研来源相关文献;6篇列为领域背景文献;另1篇中文综述作为参考综述收录。这样的组织方式,既呈现研究来路,也保留理解相关问题所需的学术背景。

各篇作者与研究内容按期刊原文记录。其中的细胞、组织、动物或人体研究,分别具有自己的研究对象。

我们沿五条线索整理

肺与气道部分共16篇,连接气道细胞身份、培养、修复及相关方法,并保留呼吸研究与公共卫生背景。肾脏部分共6篇,围绕细胞识别、损伤后的状态、类器官和修复组织资料。

女性生殖道与子宫内膜部分共8篇,我们分别保留上皮细胞研究,以及子宫内膜、月经血来源细胞的背景文献。不同来源和类型的细胞,在书目中按原研究对象呈现。

细胞信号与系统生物学部分共6篇,覆盖受体、信号调控、蛋白互作与体尺寸等基础问题;另有1篇肝再生研究,作为另一类组织与细胞工作的来源记录。

科研来源为我们的材料与转化工作提供背景。CELLshot等具体产品的外用表现,则通过相应的成品评价单独介绍。

完整书目

肺与气道再生

  1. Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy
    2024 · Sci Transl Med · 科研来源相关文献
    DOI:10.1126/scitranslmed.adi3360

  2. Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation
    2018 · Protein Cell · 科研来源相关文献
    DOI:10.1007/s13238-018-0506-y

  3. p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration
    2015 · Nature · 科研来源相关文献
    DOI:10.1038/nature13903

  4. Control of airway basal stem cell-mediated lung repair by TGF-β signaling
    2026 · Sci Adv · 科研来源相关文献
    DOI:10.1126/sciadv.adz1519

  5. Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions
    2019 · Stem Cells Int · 科研来源相关文献
    DOI:10.1155/2019/7123078

  6. Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice
    2019 · Stem Cell Res Ther · 科研来源相关文献
    DOI:10.1186/s13287-019-1257-2

  7. Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS-CoV-2
    2020 · Am J Respir Crit Care Med · 科研来源相关文献
    DOI:10.1164/rccm.202001-0179LE

  8. Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection
    2020 · EMBO Mol Med · 科研来源相关文献
    DOI:10.15252/emmm.201810233

  9. Single-cell analysis identified lung progenitor cells in COVID-19 patients
    2020 · Cell Prolif · 科研来源相关文献
    DOI:10.1111/cpr.12931

  10. Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease
    2021 · Cell Prolif · 科研来源相关文献
    DOI:10.1111/cpr.13046

  11. Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation
    2021 · Stem Cells Int · 科研来源相关文献
    DOI:10.1155/2021/9974635

  12. The Effect of Strict Lockdown on Omicron SARS-CoV-2 Variant Transmission in Shanghai
    2022 · Vaccines (Basel) · 科研来源相关文献
    DOI:10.3390/vaccines10091392

  13. Hypoxic conditions promote a proliferative, poorly differentiated phenotype in COPD lung tissue progenitor cells in vitro
    2023 · Exp Lung Res · 科研来源相关文献
    DOI:10.1080/01902148.2022.2158404

  14. Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial
    2024 · Cell Rep Med · 科研来源相关文献
    DOI:10.1016/j.xcrm.2024.101819

  15. Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
    2025 · Elife · 科研来源相关文献
    DOI:10.7554/eLife.102451

  16. Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
    2025 · Nat Commun · 科研来源相关文献
    DOI:10.1038/s41467-025-56501-w

肾脏再生

  1. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy
    2018 · Life Sci · 科研来源相关文献
    DOI:10.1016/j.lfs.2017.11.041

  2. Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine
    2021 · Protein Cell · 科研来源相关文献
    DOI:10.1007/s13238-020-00816-5

  3. Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
    2023 · Cell Prolif · 科研来源相关文献
    DOI:10.1111/cpr.13394

  4. Generation of renal tubular organoids from adult SOX9+ kidney progenitor cells
    2023 · Life Med · 科研来源相关文献
    DOI:10.1093/lifemedi/lnad047

  5. Urinary single-cell sequence analysis of the urinary macrophage in different outcomes of membranous nephropathy
    2023 · Clin Kidney J · 科研来源相关文献
    DOI:10.1093/ckj/sfad132

  6. WT1+ glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
    2023 · Theranostics · 科研来源相关文献
    DOI:10.7150/thno.79326

女性生殖道与子宫内膜

  1. Single-cell transcriptome profiling of the vaginal epithelium reveals the heterogeneity of suprabasal cells
    2023 · Precis Clin Med · 科研来源相关文献
    DOI:10.1093/pcmedi/pbad006

  2. Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium
    2021 · Cell Regen · 科研来源相关文献
    DOI:10.1186/s13619-021-00096-2

  3. Endometrial Stem/Progenitor Cells-Their Role in Endometrial Repair and Regeneration
    2022 · Front Reprod Health · 领域背景文献
    DOI:10.3389/frph.2021.811537

  4. Small extracellular vesicles from menstrual blood-derived mesenchymal stem cells (MenSCs) as a novel therapeutic impetus in regenerative medicine
    2021 · Stem Cell Res Ther · 领域背景文献
    DOI:10.1186/s13287-021-02511-6

  5. The multi-functional roles of menstrual blood-derived stem cells in regenerative medicine
    2019 · Stem Cell Res Ther · 领域背景文献
    DOI:10.1186/s13287-018-1105-9

  6. Multipotent menstrual blood stromal stem cells: isolation, characterization, and differentiation
    2008 · Cell Transplant · 领域背景文献
    DOI:10.3727/096368908784153922

  7. Differentiation of human menstrual blood-derived endometrial mesenchymal stem cells into oocyte-like cells
    2016 · Acta Biochim Biophys Sin (Shanghai) · 领域背景文献
    DOI:10.1093/abbs/gmw090

  8. Plasticity of human menstrual blood stem cells derived from the endometrium
    2011 · J Zhejiang Univ Sci B · 领域背景文献
    DOI:10.1631/jzus.B1100015

细胞信号与系统生物学

  1. Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization
    2009 · Proc Natl Acad Sci U S A · 科研来源相关文献
    DOI:10.1073/pnas.0908279106

  2. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
    2010 · Nat Cell Biol · 科研来源相关文献
    DOI:10.1038/ncb2082

  3. Monomeric type I and type III transforming growth factor-β receptors and their dimerization revealed by single-molecule imaging
    2010 · Cell Res · 科研来源相关文献
    DOI:10.1038/cr.2010.105

  4. c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor
    2013 · Mol Cell · 科研来源相关文献
    DOI:10.1016/j.molcel.2012.12.002

  5. Landscape of protein domain interactome
    2015 · Protein Cell · 科研来源相关文献
    DOI:10.1007/s13238-015-0158-0

  6. 动物体尺寸的控制机理
    2017 · 科学通报(Chinese Science Bulletin) · 参考综述
    DOI:10.1360/N972016-01099

肝再生

  1. Clonal expansion of hepatic progenitor cells and differentiation into hepatocyte-like cells
    2019 · Dev Growth Differ · 科研来源相关文献
    DOI:10.1111/dgd.12596